Gene
hspb7
- ID
- ZDB-GENE-041010-136
- Name
- heat shock protein family, member 7 (cardiovascular)
- Symbol
- hspb7 Nomenclature History
- Previous Names
-
- zgc:103426
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Involved in several processes, including Kupffer's vesicle development; cardioblast migration to the midline involved in heart rudiment formation; and determination of left/right symmetry. Used to study heart disease. Is expressed in several structures, including Kupffer's vesicle; adaxial cell; cardiovascular system; musculature system; and pericardial region. Orthologous to human HSPB7 (heat shock protein family B (small) member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103426 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| heart disease | hspb7wcm3/wcm3; twu34Tg | standard conditions | Mercer et al., 2018 |
| heart disease | hspb7wcm3/wcm3 | standard conditions | Mercer et al., 2018 |
| heart disease | hspb7wcm4/wcm4 | standard conditions | Mercer et al., 2018 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha crystallin/Hsp20 domain | Alpha crystallin/Small heat shock protein, animal type | Heat shock protein beta-7, ACD domain | HSP20-like chaperone |
|---|---|---|---|---|---|
|
UniProtKB:Q5XJD0
|
161 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids