Gene
larp6b
- ID
- ZDB-GENE-041008-244
- Name
- La ribonucleoprotein 6, translational regulator b
- Symbol
- larp6b Nomenclature History
- Previous Names
-
- im:7142825
- wu:fa55b04
- zgc:162969 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable mRNA binding activity. Predicted to act upstream of or within RNA processing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Orthologous to human LARP6 (La ribonucleoprotein 6, translational regulator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7142825 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hau et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | La domain containing protein | La-type HTH domain | Lupus La protein | SUZ-C domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A3KP60 | InterPro | 471 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
larp6b-201
(1)
|
Ensembl | 1,667 nt | ||
| mRNA |
larp6b-202
(1)
|
Ensembl | 849 nt | ||
| mRNA |
larp6b-203
(1)
|
Ensembl | 539 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-204M7 | ZFIN Curated Data | |
| Encodes | EST | fa55b04 | ||
| Encodes | EST | IMAGE:7142825 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:162969 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001089408 (1) | 1655 nt | ||
| Genomic | GenBank:CU062501 (1) | 103951 nt | ||
| Polypeptide | UniProtKB:A3KP60 (1) | 471 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | LARP6 | 15 | Amino acid sequence comparison (1) |
- Hau, H.T.A., Ogundele, O., Hibbert, A.H., Monfries, C.A.L., Exelby, K., Wood, N.J., Nevarez-Mejia, J., Carbajal, M.A., Fleck, R.A., Dermit, M., Mardakheh, F.K., Williams-Ward, V.C., Pipalia, T.G., Conte, M.R., Hughes, S.M. (2020) Maternal Larp6 controls oocyte development, chorion formation and elevation. Development (Cambridge, England). 147(4):
- Castro, J.M., Horn, D.A., Lewis, K.A. (2017) Recombinant expression and purification of the RNA-binding LARP6 proteins from fish genetic model organisms. Protein Expression and Purification. 134:147-153
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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