Gene
taf1b
- ID
- ZDB-GENE-041008-2
- Name
- TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
- Symbol
- taf1b Nomenclature History
- Previous Names
-
- si:dkey-81b15.4 (1)
- zgc:110402
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I core factor complex and RNA polymerase transcription factor SL1 complex. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to human TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | RNA polymerase I transcription initiation factor TAF1B/Rrn7 | Rrn7/TAF1B, C-terminal cyclin domain | Rrn7/TAF1B, N-terminal cyclin domain | Transcription initiation factor Rrn7, Zinc-finger |
|---|---|---|---|---|---|---|
| UniProtKB:F1R3W0 | InterPro | 576 | ||||
| UniProtKB:Q4KMI1 | InterPro | 576 | ||||
| UniProtKB:A0A8M9P2J7 | InterPro | 486 |
Interactions and Pathways
No data available
Plasmids
No data available