Gene

gsx1

ID
ZDB-GENE-041008-135
Name
GS homeobox 1
Symbol
gsx1 Nomenclature History
Previous Names
  • gsh1 (1)
  • im:7138106
  • zgc:110817 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in central nervous system development; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in central nervous system and presumptive rhombomere 3. Orthologous to human GSX1 (GS homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Coltogirone et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gsx1 Human Ortholog
No data available
Associated With gsx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Family IPR042191 GS homeobox 1/2
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length GS homeobox 1/2 Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:Q5QHS3 243
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations