Gene
ncoa1
- ID
- ZDB-GENE-041001-175
- Name
- nuclear receptor coactivator 1
- Symbol
- ncoa1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have nuclear receptor binding activity and nuclear receptor transcription coactivator activity. Predicted to be involved in cellular response to hormone stimulus and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in axis; central nervous system; intestinal bulb; liver; and presumptive diencephalon. Orthologous to human NCOA1 (nuclear receptor coactivator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017644 (7 images)
- eu1590 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Manesia et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000014 | PAS domain |
| Domain | IPR010011 | Nuclear receptor coactivator, DUF1518 |
| Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| Domain | IPR013767 | PAS fold |
| Domain | IPR014920 | Nuclear receptor coactivator, Ncoa-type, interlocking |
| Domain | IPR014935 | Nuclear receptor coactivator, receptor-binding domain |
| Domain | IPR028819 | Nuclear receptor coactivator 1, basic helix-loop-helix |
| Family | IPR017426 | Nuclear receptor coactivator |
| Homologous_superfamily | IPR009110 | Nuclear receptor coactivator, interlocking |
| Homologous_superfamily | IPR035965 | PAS domain superfamily |
| Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR037077 | Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamily |
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Nuclear receptor coactivator | Nuclear receptor coactivator 1, basic helix-loop-helix | Nuclear receptor coactivator, DUF1518 | Nuclear receptor coactivator, interlocking | Nuclear receptor coactivator, Ncoa-type, interlocking | Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamily | Nuclear receptor coactivator, receptor-binding domain | PAS domain | PAS domain superfamily | PAS fold |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PTD7
|
1349 | ||||||||||||
|
UniProtKB:A0A8M3AWF7
|
1312 |
Interactions and Pathways
No data available
Plasmids
No data available