Gene

polr1d

ID
ZDB-GENE-040930-4
Name
RNA polymerase I and III subunit D
Symbol
polr1d Nomenclature History
Previous Names
  • im:7162148
  • zgc:136449 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Involved in cartilage development; embryonic viscerocranium morphogenesis; and ribosome biogenesis. Predicted to localize to RNA polymerase I complex and RNA polymerase III complex. Used to study Treacher Collins syndrome. Human ortholog(s) of this gene implicated in Treacher Collins syndrome. Is expressed in eye; lens; midbrain hindbrain boundary; optic tectum; and pharyngeal arch. Orthologous to human POLR1D (RNA polymerase I and III subunit D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With polr1d Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Treacher Collins syndrome 2 Alliance Treacher Collins syndrome 2 613717
Associated With polr1d Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site
Domain IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain
Family IPR033898 DNA-directed RNA polymerases I and III subunit AC19
Homologous_superfamily IPR036603 RNA polymerase, RBP11-like subunit
Domain Details Per Protein
Protein Length DNA-directed RNA polymerase, RBP11-like dimerisation domain DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site DNA-directed RNA polymerases I and III subunit AC19 RNA polymerase, RBP11-like subunit
UniProtKB:Q6DRI4 112
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations