Gene

crata

ID

ZDB-GENE-040927-17

Name

carnitine O-acetyltransferase a

Symbol

crata Nomenclature History

Previous Names

hm:zeh0248
zeh0248
zgc:92317

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable carnitine O-acetyltransferase activity. Predicted to be involved in carnitine metabolic process, CoA-linked. Predicted to be located in endoplasmic reticulum and mitochondrial inner membrane. Predicted to be active in peroxisome. Is expressed in cardiac ventricle. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Orthologous to human CRAT (carnitine O-acetyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu2430 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With crata Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Neurodegeneration with brain iron accumulation 8	617917

Associated With crata Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR039551	Choline/carnitine acyltransferase domain
Family	IPR000542	Acyltransferase ChoActase/COT/CPT
Homologous_superfamily	IPR023213	Chloramphenicol acetyltransferase-like domain superfamily
Homologous_superfamily	IPR042231	Choline/Carnitine o-acyltransferase, domain 2