Gene
gpx1b
- ID
- ZDB-GENE-040912-60
- Name
- glutathione peroxidase 1b
- Symbol
- gpx1b Nomenclature History
- Previous Names
-
- wu:fd42f12
- wu:fj22d06
- zgc:101700
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have glutathione peroxidase activity. Predicted to be involved in several processes, including hydrogen peroxide catabolic process; response to hydrogen peroxide; and response to selenium ion. Predicted to localize to cytosol and mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Is expressed in digestive system; otic vesicle; and sensory system. Orthologous to human GPX1 (glutathione peroxidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101700 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hemolytic anemia due to glutathione peroxidase deficiency | 614164 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glutathione peroxidase | Glutathione peroxidase active site | Thioredoxin-like superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M1N295
|
190 |
Interactions and Pathways
No data available
Plasmids
No data available