Gene
ect2
- ID
- ZDB-GENE-040831-2
- Name
- epithelial cell transforming 2
- Symbol
- ect2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Is predicted to enable guanyl-nucleotide exchange factor activity. Involved in activation of GTPase activity; mitotic cytokinesis; and nervous system development. Acts upstream of or within cytokinetic process. Predicted to be located in cytoplasm. Is expressed in midbrain. Orthologous to human ECT2 (epithelial cell transforming 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001357 | BRCT domain |
| Family | IPR026817 | Guanine nucleotide exchange factor Ect2 |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036420 | BRCT domain superfamily |
Domain Details Per Protein
| Protein | Length | BRCT domain | BRCT domain superfamily | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Guanine nucleotide exchange factor Ect2 | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QVS6
|
976 | |||||||
|
UniProtKB:A0A2R8Q1Z1
|
980 | |||||||
|
UniProtKB:Q4V9L0
|
976 | |||||||
|
UniProtKB:A0A2R8RJY1
|
944 | |||||||
|
UniProtKB:A0A0R4IKD5
|
1012 | |||||||
|
UniProtKB:Q6DRB9
|
878 |
Interactions and Pathways
No data available
Plasmids
No data available