Gene
ect2
- ID
- ZDB-GENE-040831-2
- Name
- epithelial cell transforming 2
- Symbol
- ect2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within cytokinetic process. Predicted to be located in cytoplasm. Predicted to be active in cell cortex and nucleus. Is expressed in midbrain. Orthologous to human ECT2 (epithelial cell transforming 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology domain |
| Domain | IPR001357 | BRCT domain |
| Domain | IPR049395 | ECT2, PH domain |
| Domain | IPR049396 | ECT2, BRCT0 domain |
| Family | IPR026817 | Guanine nucleotide exchange factor Ect2 |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036420 | BRCT domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | BRCT domain | BRCT domain superfamily | Dbl homology (DH) domain superfamily | Dbl homology domain | ECT2, BRCT0 domain | ECT2, PH domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Guanine nucleotide exchange factor Ect2 | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B1T9 | InterPro | 946 | |||||||||
| UniProtKB:Q6DRB9 | InterPro | 878 | |||||||||
| UniProtKB:F1QVS6 | InterPro | 976 | |||||||||
| UniProtKB:A0A2R8Q1Z1 | InterPro | 980 | |||||||||
| UniProtKB:A0A8M2B2N3 | InterPro | 1012 | |||||||||
| UniProtKB:A0AB32U339 | InterPro | 944 | |||||||||
| UniProtKB:A0AB32U4B0 | InterPro | 910 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available