epb41l3a

ID

ZDB-GENE-040822-8

Name

erythrocyte membrane protein band 4.1-like 3a

Symbol

epb41l3a Nomenclature History

Previous Names

zgc:92004
zmp:0000000522 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be involved in actomyosin structure organization. Predicted to be active in cytoskeleton and plasma membrane. Is expressed in nervous system; optic cup; and trigeminal placode. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma. Orthologous to human EPB41L3 (erythrocyte membrane protein band 4.1 like 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7152107 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Fierro et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With epb41l3a Human Ortholog

No data available

Associated With epb41l3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019747	FERM conserved site
Domain	IPR000299	FERM domain
Domain	IPR007477	SAB domain
Domain	IPR008379	Band 4.1, C-terminal
Domain	IPR014847	FERM adjacent
Domain	IPR018979	FERM, N-terminal
Domain	IPR018980	FERM, C-terminal PH-like domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Domain	IPR030691	Band 4.1-like protein 3, FERM domain, F1 sub-domain
Family	IPR000798	Ezrin/radixin/moesin-like
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PFY0	InterPro	1073
UniProtKB:A0A8M9P5U6	InterPro	1088
UniProtKB:Q68EI5	InterPro	826
UniProtKB:A0A8M9PLP9	InterPro	1053
UniProtKB:A0A8M9P5V2	InterPro	903
UniProtKB:A0A8M9PU07	InterPro	937
UniProtKB:A0A8M9PFZ0	InterPro	861
UniProtKB:A0A8M9PXF8	InterPro	735
UniProtKB:A0A8M9PXF4	InterPro	972
UniProtKB:A0A8M9P5U9	InterPro	1177
UniProtKB:A0AB13ABU7	InterPro	922
UniProtKB:A0AB32TCP1	InterPro	861
UniProtKB:A0AB32TE72	InterPro	957
UniProtKB:A0AB32TGR6	InterPro	752
UniProtKB:A0AC58IQ67	InterPro	1127
UniProtKB:A0AC58IQ69	InterPro	1162
UniProtKB:A0AC58IQ70	InterPro	1142
UniProtKB:A0AC58IQ71	InterPro	1142
UniProtKB:A0AC58IQ72	InterPro	888
UniProtKB:A0AC58IQ73	InterPro	1061
UniProtKB:A0AC58IQ75	InterPro	1162
UniProtKB:A0AC58IQ76	InterPro	1162
UniProtKB:A0AC58IQ77	InterPro	1038
UniProtKB:A0AC58IQ78	InterPro	1127
UniProtKB:A0AC58IQ79	InterPro	868
UniProtKB:A0AC58IQ80	InterPro	1061
UniProtKB:A0AC58IQ82	InterPro	1011
UniProtKB:A0AC58IQ83	InterPro	853
UniProtKB:A0AC58IQ85	InterPro	1026
UniProtKB:A0AC58IQ86	InterPro	992
UniProtKB:A0AC58IQ87	InterPro	1026
UniProtKB:A0AC58IQ88	InterPro	1046
UniProtKB:A0AC58IQ89	InterPro	992
UniProtKB:A0AC58IQ90	InterPro	787
UniProtKB:A0AC58IQ91	InterPro	992
UniProtKB:A0AC58IQ92	InterPro	1046
UniProtKB:A0AC58IQ93	InterPro	876
UniProtKB:A0AC58IQ94	InterPro	876
UniProtKB:A0AC58IQ95	InterPro	977
UniProtKB:A0AC58IQ96	InterPro	737
UniProtKB:A0AC58IQ97	InterPro	1046
UniProtKB:A0AC58IQ98	InterPro	1011
UniProtKB:A0AC58IQ99	InterPro	1026
UniProtKB:A0AC58IQA0	InterPro	1011
UniProtKB:A0AC58IQA2	InterPro	942
UniProtKB:A0AC58IQA3	InterPro	841
UniProtKB:A0AC58IQA4	InterPro	826
UniProtKB:A0AC58IQA6	InterPro	957
UniProtKB:A0AC58IQA7	InterPro	841
UniProtKB:A0AC58IQA8	InterPro	772
UniProtKB:A0AC58IQA9	InterPro	861
UniProtKB:A0AC58IQB0	InterPro	957
UniProtKB:A0AC58IQB1	InterPro	942