Gene

gspt1

ID

ZDB-GENE-040822-36

Name

G1 to S phase transition 1

Symbol

gspt1 Nomenclature History

Previous Names

zgc:91975 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Is expressed in axial mesoderm; immature eye; myotome; optic primordium; and retina. Orthologous to several human genes including GSPT1 (G1 to S phase transition 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:91975 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gspt1 Human Ortholog

No data available

Associated With gspt1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR009818	PAM2 motif
Conserved_site	IPR031157	Tr-type G domain, conserved site
Domain	IPR000795	Translational (tr)-type GTP-binding domain
Domain	IPR004161	Translation elongation factor EFTu-like, domain 2
Domain	IPR054696	GTP-eEF1A, C-terminal domain
Family	IPR050100	Translation factor GTPase superfamily members
Homologous_superfamily	IPR009000	Translation protein, beta-barrel domain superfamily
Homologous_superfamily	IPR009001	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase