nfil3

ID

ZDB-GENE-040822-28

Name

nuclear factor, interleukin 3 regulated

Symbol

nfil3 Nomenclature History

Previous Names

E4BP4 (1)
ze4bp4-1 (1)
zgc:100867

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within heart development and myeloid cell development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in brain; margin; retina; and tail bud. Orthologous to human NFIL3 (nuclear factor, interleukin 3 regulated).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7137109 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Progatzky et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nfil3 Human Ortholog

No data available

Associated With nfil3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Domain	IPR010533	Vertebrate interleukin-3 regulated transcription factor
Domain	IPR047106	Nuclear factor interleukin-3-regulated protein-like , bZIP domain
Family	IPR016743	Nuclear factor interleukin-3-regulated protein
Family	IPR047229	Nuclear factor interleukin-3-regulated protein-like
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily