Gene
emp2
- ID
- ZDB-GENE-040822-24
- Name
- epithelial membrane protein 2
- Symbol
- emp2 Nomenclature History
- Previous Names
-
- zgc:100935
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Involved in regulation of glomerular filtration. Predicted to localize to cytoplasm; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 10. Is expressed in blood vessel; orbit; pectoral fin; pharyngeal arch; and pronephros. Orthologous to human EMP2 (epithelial membrane protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145711 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephrotic syndrome type 10 | Alliance | Nephrotic syndrome, type 10 | 615861 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PMP-22/EMP/MP20 | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|
|
UniProtKB:A0A8M9PUL4
|
161 | ||
|
UniProtKB:Q68EL5
|
153 |
Interactions and Pathways
No data available
Plasmids
No data available