Gene
gga1
- ID
- ZDB-GENE-040822-13
- Name
- golgi-associated, gamma adaptin ear containing, ARF binding protein 1
- Symbol
- gga1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi to plasma membrane transport and protein localization to cell surface. Predicted to act upstream of or within intracellular protein transport and vesicle-mediated transport. Predicted to be located in Golgi apparatus and early endosome membrane. Predicted to be active in trans-Golgi network. Orthologous to human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6912200 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa11719 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ADP-ribosylation factor-binding protein GGA1-3 | Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain | Clathrin adaptor, appendage, Ig-like subdomain superfamily | ENTH/VHS | Gamma-adaptin ear (GAE) domain | GAT domain | GAT domain superfamily | N-terminal extension of GAT domain | VHS domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8QEJ6 | InterPro | 635 | |||||||||
| UniProtKB:A9JT96 | InterPro | 568 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-156N14 | ZFIN Curated Data | |
| Encodes | EST | fb33h10 | ||
| Encodes | EST | IMAGE:6912200 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:101044 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:174734 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001004000 (1) | 3111 nt | ||
| Genomic | GenBank:BX004829 (1) | 231581 nt | ||
| Polypeptide | UniProtKB:A0A2R8QEJ6 (1) | 635 aa |
- Garcia-Concejo, A., Larhammar, D. (2021) Protein kinase C family evolution in jawed vertebrates. Developmental Biology. 479:77-90
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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