Gene

b4galt7

ID

ZDB-GENE-040727-3

Name

xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

Symbol

b4galt7 Nomenclature History

Previous Names

zgc:110571

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have transferase activity, transferring glycosyl groups. Predicted to be involved in carbohydrate metabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and Ehlers-Danlos syndrome progeroid type. Orthologous to human B4GALT7 (beta-1,4-galactosyltransferase 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Delbaere et al., 2019

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 10 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With b4galt7 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Ehlers-Danlos syndrome spondylodysplastic type 1	Alliance	Ehlers-Danlos syndrome, spondylodysplastic type, 1	130070

Associated With b4galt7 Via Experimental Models

Human Disease	Fish	Conditions	Citations
Ehlers-Danlos syndrome	b4galt7^{hi1516Tg/hi1516Tg}	standard conditions	Nissen et al., 2006
Ehlers-Danlos syndrome	b4galt7^{hi4063aTg/hi4063aTg}	standard conditions	Nissen et al., 2006

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR027791	Galactosyltransferase, C-terminal
Domain	IPR027995	Galactosyltransferase, N-terminal
Family	IPR003859	Beta-1,4-galactosyltransferase
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases