ZFIN is now using GRCz12tu for Genomic Data
Gene
cox6c
- ID
- ZDB-GENE-040724-95
- Name
- cytochrome c oxidase subunit 6C
- Symbol
- cox6c Nomenclature History
- Previous Names
-
- si:ch211-239j9.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Duggan et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome c oxidase subunit VIc | Mitochondrial cytochrome c oxidase subunit VIc/VIIs | Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q6ZM23 | InterPro | 76 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-239J9 | ||
| Encodes | cDNA | MGC:171774 | ZFIN Curated Data |
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| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001204124 (1) | 480 nt | ||
| Genomic | GenBank:AL929108 (1) | 161277 nt | ||
| Polypeptide | UniProtKB:Q6ZM23 (1) | 76 aa |
No data available
- Ganguly, A., Padhan, D.K., Sengupta, A., Chakraborty, P., Sen, M. (2023) CCN6 influences transcription and controls mitochondrial mass and muscle organization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 37:e22815e22815
- Brandão, A.S., Borbinha, J., Pereira, T., Brito, P.H., Lourenço, R., Bensimon-Brito, A., Jacinto, A. (2022) A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration. eLIFE. 11
- Wang, X., Ren, Y., Li, J., Ji, Z., Chen, F., Wang, X. (2020) Identification of the 14-3-3 β/α-A protein as a novel maternal peptidoglycan-binding protein that protects embryos of zebrafish against bacterial infections. Developmental and comparative immunology. 114:103867
- Chen, M., Luo, Y., Xu, J., Chang, M.X., Liu, J.X. (2019) Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival. Frontiers in immunology. 10:2599
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Chen, W.C., Wang, Z., Missinato, M.A., Park, D.W., Long, D.W., Liu, H.J., Zeng, X., Yates, N.A., Kim, K., Wang, Y. (2016) Decellularized zebrafish cardiac extracellular matrix induces mammalian heart regeneration. Science advances. 2:e1600844
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Duggan, A.T., Kocha, K.M., Monk, C.T., Bremer, K., and Moyes, C.D. (2011) Coordination of cytochrome c oxidase gene expression in the remodelling of skeletal muscle. The Journal of experimental biology. 214(11):1880-1887
- Little, A.G., Kocha, K.M., Lougheed, S.C., and Moyes, C.D. (2010) Evolution of the Nuclear-Encoded Cytochrome Oxidase Subunits in Vertebrates. Physiological Genomics. 42(1):76-84
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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