Gene
gpr132b
- ID
- ZDB-GENE-040724-83
- Name
- G protein-coupled receptor 132b
- Symbol
- gpr132b Nomenclature History
- Previous Names
-
- si:ch211-20b12.2
- zgc:136260
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Acts upstream of or within response to acidic pH. Predicted to be located in plasma membrane. Is expressed in several structures, including digestive system; hematopoietic system; nervous system; pleuroperitoneal region; and scale. Orthologous to human GPR132 (G protein-coupled receptor 132).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Xu et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-gpr132b | N/A | Xu et al., 2016 |
| MO2-gpr132b | N/A | Lahvic et al., 2018 |
1 - 2 of 2
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
| UniProtKB:A0A0R4IEK2 | InterPro | 373 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gpr132b-201
(1)
|
Ensembl | 1,726 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-164O4 | ZFIN Curated Data | |
| Contained in | BAC | CH211-20B12 | ||
| Encodes | cDNA | MGC:136260 | ZFIN Curated Data |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001025547 (1) | 1737 nt | ||
| Genomic | GenBank:CU861664 (1) | 74571 nt | ||
| Polypeptide | UniProtKB:A0A0R4IEK2 (1) | 373 aa |
- Lou, L., Yu, T., Dai, Y., Zhao, S., Feng, S., Xu, J., Wen, Z. (2022) Mafba and Mafbb regulate microglial colonization of zebrafish brain via controlling chemotaxis receptor expression. Proceedings of the National Academy of Sciences of the United States of America. 119:e2203273119
- Xia, J., Kang, Z., Xue, Y., Ding, Y., Gao, S., Zhang, Y., Lv, P., Wang, X., Ma, D., Wang, L., Han, J.J., Liu, F. (2021) A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 118(14):
- Lahvic, J.L., Ammerman, M., Li, P., Blair, M.C., Stillman, E.R., Fast, E.M., Robertson, A.L., Christodoulou, C., Perlin, J.R., Yang, S., Chiang, N., Norris, P.C., Daily, M.L., Redfield, S.E., Chan, I.T., Chatrizeh, M., Chase, M.E., Weis, O., Zhou, Y., Serhan, C.N., Zon, L.I. (2018) Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America. 115(37):9252-9257
- Ichijo, Y., Mochimaru, Y., Azuma, M., Satou, K., Negishi, J., Nakakura, T., Oshima, N., Mogi, C., Sato, K., Matsuda, K., Okajima, F., Tomura, H. (2016) Two zebrafish G2A homologs activate multiple intracellular signaling pathways in acidic environment. Biochemical and Biophysical Research Communications. 469(1):81-6
- Xu, J., Wang, T., Wu, Y., Jin, W., Wen, Z. (2016) Microglia Colonization of Developing Zebrafish Midbrain Is Promoted by Apoptotic Neuron and Lysophosphatidylcholine. Developmental Cell. 38(2):214-22
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 6 of 6
Show