Gene
il20ra
- ID
- ZDB-GENE-040724-249
- Name
- interleukin 20 receptor, alpha
- Symbol
- il20ra Nomenclature History
- Previous Names
-
- crfb8
- im:7156745
- si:ch211-272f15.1
- zgc:158705
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human IL20RA (interleukin 20 receptor subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7156745 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003961 | Fibronectin type III |
Domain | IPR015373 | Interferon/interleukin receptor domain |
Family | IPR050650 | Type II Cytokine and Tissue Factor Receptors |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
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Domain Details Per Protein
Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Interferon/interleukin receptor domain | Type II Cytokine and Tissue Factor Receptors |
---|---|---|---|---|---|---|---|
UniProtKB:F1RBF1 | InterPro | 492 | |||||
UniProtKB:A0A8M2B761 | InterPro | 491 | |||||
UniProtKB:A1L286 | InterPro | 272 | |||||
UniProtKB:A0FJI3 | InterPro | 492 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
il20ra-201
(1)
|
Ensembl | 2,613 nt | ||
ncRNA |
il20ra-002
(1)
|
Ensembl | 1,098 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-272F15 | ||
Contained in | Fosmid | ZFOS-404D2 | ZFIN Curated Data | |
Encodes | EST | IMAGE:7156745 | Thisse et al., 2004 | |
Encodes | cDNA | MGC:158705 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001079676 (1) | 2626 nt | ||
Genomic | GenBank:BX072559 (2) | 156196 nt | ||
Polypeptide | UniProtKB:A0FJI3 (1) | 492 aa |
- Deng, Y.H., Li, B., Chen, S.N., Ren, L., Zhang, B.D., Liu, L.H., Liu, S., Nie, P. (2023) Molecular characterization of nineteen cytokine receptor family B (CRFB) members, CRFB1, CRFB2, CRFB4-17, with three CRFB9 and two CRFB14 in a cyprinid fish, the blunt snout bream Megalobrama amblycephala. Developmental and comparative immunology. 145:104725
- Zheng, S.Y., Shao, X., Qi, Z., Yan, M., Tao, M.H., Wu, X.M., Zhang, L., Ma, J., Li, A., Chang, M.X. (2023) Zebrafish nos2a benefits bacterial proliferation via suppressing ROS and inducing NO production to impair the expressions of inflammatory cytokines and antibacterial genes. Fish & shellfish immunology. 142:109178
- Banu, S., Gaur, N., Nair, S., Ravikrishnan, T., Khan, S., Mani, S., Bharathi, S., Mandal, K., Kuram, N.A., Vuppaladadium, S., Ravi, R., Murthy, C.L.N., Quoseena, M., Babu, N.S., Idris, M.M. (2022) Transcriptomic and proteomic analysis of epimorphic regeneration in zebrafish caudal fin tissue. Genomics. 114(2):110300
- Chen, S.N., Gan, Z., Hou, J., Yang, Y.C., Huang, L., Huang, B., Wang, S., Nie, P. (2022) Identification and establishment of type IV interferon and the characterization of interferon-υ including its class II cytokine receptors IFN-υR1 and IL-10R2. Nature communications. 13:999
- Pozo-Morales, M., Garteizgogeascoa, I., Perazzolo, C., So, J., Shin, D., Singh, S.P. (2022) In vivo imaging of calcium dynamics in zebrafish hepatocytes. Hepatology (Baltimore, Md.). 77(3):789-801
- Ray, A., Bhaduri, A., Srivastava, N., Mazumder, S. (2017) Identification of novel signature genes attesting arsenic-induced immune alterations in adult zebrafish (Danio rerio). Journal of hazardous materials. 321:121-131
- Chen, H., Liu, W., Wang, B., Mao, H., Sun, Z., Hou, Q., Mi, Y., Fan, L., Hu, C. (2015) Cloning, identification of the two cytokine receptor family B subunits CRFB1 and CRFB5 from grass carp (Ctenopharyngodon idella). Fish & shellfish immunology. 45(2):211-20
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Aggad, D., Stein, C., Sieger, D., Mazel, M., Boudinot, P., Herbomel, P., Levraud, J.P., Lutfalla, G., and Leptin, M. (2010) In Vivo Analysis of Ifn-γ1 and Ifn-γ2 Signaling in Zebrafish. Journal of immunology (Baltimore, Md. : 1950). 185(11):6774-6782
- Levraud, J.P., Boudinot, P., Colin, I., Benmansour, A., Peyriéras, N., Herbomel, P., and Lutfalla, G. (2007) Identification of the Zebrafish IFN Receptor: Implications for the Origin of the Vertebrate IFN System. Journal of immunology (Baltimore, Md. : 1950). 178(7):4385-4394
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