Gene

hdhd3

ID

ZDB-GENE-040724-118

Name

haloacid dehalogenase-like hydrolase domain containing 3

Symbol

hdhd3 Nomenclature History

Previous Names

si:ch211-10e8.6
zgc:136363
zgc:158529

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to be active in nucleus. Orthologous to human HDHD3 (haloacid dehalogenase like hydrolase domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa9862	Allele with one point mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

1 - 1 of 1

Show

Sequence Targeting Reagents

No data available

Human Disease

Associated With hdhd3 Human Ortholog

No data available

Associated With hdhd3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR006439	HAD hydrolase, subfamily IA
Family	IPR011949	HAD-superfamily hydrolase, subfamily IA, REG-2-like
Family	IPR051828	HAD-like hydrolase domain-containing protein
Homologous_superfamily	IPR023214	HAD superfamily
Homologous_superfamily	IPR036412	HAD-like superfamily

1 - 5 of 6 Show all

Domain Details Per Protein

Protein	Additional Resources	Length	HAD hydrolase, subfamily IA	HAD-like hydrolase domain-containing protein	HAD-like superfamily	HAD superfamily	HAD-superfamily hydrolase, subfamily IA, REG-2-like	HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily
UniProtKB:Q7T012	InterPro	242

1 - 1 of 1

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 6

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	hdhd3-201 (1) Ensembl	Ensembl		1,395 nt	Select Tool ZFIN BLAST
mRNA	hdhd3-202 (1) Ensembl	Ensembl		5,391 nt	Select Tool ZFIN BLAST

1 - 2 of 2

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH211-10E8	AL732598
Encodes	cDNA	MGC:136363	BC116519	ZFIN Curated Data
Encodes	cDNA	MGC:158529	BC133114	ZFIN Curated Data

1 - 3 of 3

Show

Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001045267 (1)	1262 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:AL732598 (2)	88982 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q7T012 (1)	242 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	HDHD3	9	Ensembl:ENSG00000119431 Gene:81932 HGNC:28171	Amino acid sequence comparison (1)
Mouse	Hdhd3	4	Ensembl:ENSMUSG00000038422 Gene:72748 MGI:1919998	Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

1 - 1 of 1

Show