Gene

mpc1

ID
ZDB-GENE-040718-94
Name
mitochondrial pyruvate carrier 1
Symbol
mpc1 Nomenclature History
Previous Names
  • zgc:92707
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have pyruvate transmembrane transporter activity. Involved in digestive tract development. Predicted to localize to integral component of mitochondrial inner membrane. Is expressed in several structures, including digestive system; female organism; head; pectoral fin; and vasculature. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Sandoval et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mpc1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitochondrial pyruvate carrier deficiency Alliance Mitochondrial pyruvate carrier deficiency 614741
Associated With mpc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005336 Mitochondrial pyruvate carrier
Domain Details Per Protein
Protein Length Mitochondrial pyruvate carrier
UniProtKB:F1Q6Z3 109
UniProtKB:Q6DGZ7 109
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations