Gene

ift74

ID
ZDB-GENE-040718-81
Name
intraflagellar transport 74
Symbol
ift74 Nomenclature History
Previous Names
  • zgc:92052
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have beta-tubulin binding activity. Involved in gastrulation and pronephric proximal tubule development. Predicted to localize to intraciliary transport particle B. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome. Orthologous to human IFT74 (intraflagellar transport 74).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhu et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift74 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Bardet-Biedl syndrome 22 Alliance Bardet-Biedl syndrome 22 617119
spermatogenic failure 58 Alliance Spermatogenic failure 58 619585
Joubert syndrome 40 619582
Associated With ift74 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR029602 Intraflagellar transport protein 74
Domain Details Per Protein
Protein Length Intraflagellar transport protein 74
UniProtKB:A0A8M9PXA7 583
UniProtKB:Q6DHU7 486
UniProtKB:A0A8M9Q8D0 603
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations