ZFIN is now using GRCz12tu for Genomic Data
Gene
thop1
- ID
- ZDB-GENE-040718-47
- Name
- thimet oligopeptidase 1
- Symbol
- thop1 Nomenclature History
- Previous Names
-
- fb74b01
- wu:fb74b01
- zgc:92139 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be active in mitochondrial intermembrane space. Is expressed in lens. Orthologous to human THOP1 (thimet oligopeptidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137009 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001567 | Peptidase M3A/M3B catalytic domain |
| Family | IPR045090 | Peptidase M3A/M3B |
| Homologous_superfamily | IPR024077 | Neurolysin/Thimet oligopeptidase, domain 2 |
| Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
| Homologous_superfamily | IPR024080 | Neurolysin/Thimet oligopeptidase, N-terminal |
Domain Details Per Protein
| Protein | Additional Resources | Length | Metallopeptidase, catalytic domain superfamily | Neurolysin/Thimet oligopeptidase, domain 2 | Neurolysin/Thimet oligopeptidase, N-terminal | Peptidase M3A/M3B | Peptidase M3A/M3B catalytic domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7EZ90 | InterPro | 707 | |||||
| UniProtKB:Q6DHR6 | InterPro | 686 | |||||
| UniProtKB:A0AC58GQ34 | InterPro | 707 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers