ZFIN is now using GRCz12tu for Genomic Data
Gene
pde6d
- ID
- ZDB-GENE-040718-463
- Name
- phosphodiesterase 6D, cGMP-specific, rod, delta
- Symbol
- pde6d Nomenclature History
- Previous Names
-
- zgc:92605 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTPase inhibitor activity. Acts upstream of or within eye development and kidney development. Predicted to be located in cytoplasmic vesicle membrane and cytosol. Predicted to be active in cytoplasm. Is expressed in epiphysis; male organism; olfactory bulb; olfactory placode; and retina. Human ortholog(s) of this gene implicated in Joubert syndrome 22. Orthologous to human PDE6D (phosphodiesterase 6D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92605 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Thomas et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Joubert syndrome 22 | Alliance | Joubert syndrome 22 | 615665 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR008015 | GMP phosphodiesterase, delta subunit |
| Family | IPR017287 | Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR037036 | GMP phosphodiesterase, delta subunit superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set | Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit |
|---|---|---|---|---|---|---|
| UniProtKB:Q6DH83 | InterPro | 150 | ||||
| UniProtKB:A0AC58JR06 | InterPro | 131 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers