Gene

bcat2

ID

ZDB-GENE-040718-425

Name

branched chain amino-acid transaminase 2, mitochondrial

Symbol

bcat2 Nomenclature History

Previous Names

fb37h12
wu:fb37h12
zgc:91919

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have branched-chain-amino-acid transaminase activity. Predicted to be involved in leucine biosynthetic process and valine biosynthetic process. Predicted to localize to mitochondrion. Orthologous to human BCAT2 (branched chain amino acid transaminase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bcat2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Hypervalinemia or hyperleucine-isoleucinemia	618850

Associated With bcat2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018300	Aminotransferase, class IV, conserved site
Family	IPR001544	Aminotransferase class IV
Family	IPR005786	Branched-chain amino acid aminotransferase II
Family	IPR033939	Branched-chain aminotransferase
Homologous_superfamily	IPR036038	Aminotransferase-like, PLP-dependent enzymes
Homologous_superfamily	IPR043131	Branched-chain-amino-acid aminotransferase-like, N-terminal
Homologous_superfamily	IPR043132	Branched-chain-amino-acid aminotransferase-like, C-terminal

Domain Details Per Protein

Protein	Length	Aminotransferase class IV	Aminotransferase, class IV, conserved site	Aminotransferase-like, PLP-dependent enzymes	Branched-chain amino acid aminotransferase II	Branched-chain-amino-acid aminotransferase-like, C-terminal	Branched-chain-amino-acid aminotransferase-like, N-terminal	Branched-chain aminotransferase
UniProtKB:E9QCQ6 InterPro	406
UniProtKB:E9QFU8 InterPro	391

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	bcat2-202 (1) Ensembl	Havana	3252 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	bcat2-203 (1) Ensembl	Havana	3281 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations