Gene

ap4m1

ID
ZDB-GENE-040718-421
Name
adaptor related protein complex 4 subunit mu 1
Symbol
ap4m1 Nomenclature History
Previous Names
  • si:ch211-237l4.1
  • zgc:91931 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to be involved in Golgi to lysosome transport and protein targeting. Predicted to localize to cytoplasmic vesicle and trans-Golgi network. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Orthologous to human AP4M1 (adaptor related protein complex 4 subunit mu 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ap4m1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 50 Alliance Spastic paraplegia 50, autosomal recessive 612936
Associated With ap4m1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022775 AP complex, mu/sigma subunit
Domain IPR028565 Mu homology domain
Family IPR001392 Clathrin adaptor, mu subunit
Homologous_superfamily IPR011012 Longin-like domain superfamily
Homologous_superfamily IPR036168 AP-2 complex subunit mu, C-terminal superfamily
Domain Details Per Protein
Protein Length AP-2 complex subunit mu, C-terminal superfamily AP complex, mu/sigma subunit Clathrin adaptor, mu subunit Longin-like domain superfamily Mu homology domain
UniProtKB:Q7SZZ7 442
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations