Gene
egln1b
- ID
- ZDB-GENE-040718-338
- Name
- egl-9 family hypoxia-inducible factor 1b
- Symbol
- egln1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have L-ascorbic acid binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in familial erythrocytosis 3; polycythemia; and renal cell carcinoma. Orthologous to human EGLN1 (egl-9 family hypoxia inducible factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6892887 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial erythrocytosis 3 | Alliance | Erythrocytosis, familial, 3 | 609820 |
| [Hemoglobin, high altitude adaptation] | 609070 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Oxoglutarate/iron-dependent dioxygenase | Prolyl 4-hydroxylase, alpha subunit | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Zinc finger, MYND-type |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q756
|
318 | ||||
|
UniProtKB:F6P6J7
|
358 | ||||
|
UniProtKB:Q6DHH3
|
335 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
egln1b-201
(1)
|
Havana | 2335 nt | |
| mRNA |
egln1b-202
(1)
|
Havana | 864 nt |
Interactions and Pathways
No data available
Plasmids
No data available