Gene
narf
- ID
- ZDB-GENE-040718-31
- Name
- nuclear prelamin A recognition factor
- Symbol
- narf Nomenclature History
- Previous Names
-
- fa03c01
- wu:fa03c01
- zgc:92186 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable lamin binding activity. Predicted to be located in nucleus. Predicted to be active in lamin filament. Orthologous to human NARF (nuclear prelamin A recognition factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6900883 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa6266 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa22143 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa27988 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa35336 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa35338 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytosolic Fe-S Cluster Assembly Factor | Iron hydrogenase | Iron hydrogenase, large subunit, C-terminal | Iron hydrogenase, small subunit |
|---|---|---|---|---|---|---|
| UniProtKB:Q6DHP6 | InterPro | 465 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-13L14 | ZFIN Curated Data | |
| Encodes | EST | fa03c01 | ||
| Encodes | EST | IMAGE:6900883 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:92186 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002342 (1) | 2040 nt | ||
| Genomic | GenBank:CR735103 (1) | 126042 nt | ||
| Polypeptide | UniProtKB:Q6DHP6 (1) | 465 aa |
- Xu, S., Hong, J., Dongye, M., Lin, J., Xue, R., Huang, Z., Xu, J., Zhang, Y., Leung, A.Y., Shen, J., Zhang, W., Liu, W. (2025) The synergistic effect of c-Myb hyperactivation and Pu.1 deficiency induces Pelger-Huët anomaly and promotes sAML. Proceedings of the National Academy of Sciences of the United States of America. 122:e2416121122e2416121122
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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