Gene
tspan36
- ID
- ZDB-GENE-040718-248
- Name
- tetraspanin 36
- Symbol
- tspan36 Nomenclature History
- Previous Names
-
- dali
- tspan3c (1)
- sb:cb666
- zgc:100919
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Acts upstream of or within pigmentation. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; gonad; heart; optic vesicle; and pigment cell.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb666 (11 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la016338Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa7616 | Allele with one point mutation | Unknown | Missense | ENU | |
| sa21320 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41232 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| wpr21e1 | unknown | Unknown | Unknown | not specified |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Tetraspanin, animals | Tetraspanin, EC2 domain superfamily | Tetraspanin/Peripherin |
|---|---|---|---|---|---|
| UniProtKB:Q6NWG0 | InterPro | 243 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tspan36-201
(1)
|
Ensembl | 1,496 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(tspan36:EGFP) |
|
| 1 | (2) | |
| Tg(tspan36:tspan36) |
|
|
| 1 | (2) |
| Tg(tspan36:tspan36-EGFP) |
|
|
| 1 | (3) |
| Tg(tspan36:tspan36_I18R-EGFP) |
|
|
| 1 | (2) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-222K8 | ZFIN Curated Data | |
| Contained in | BAC | CH211-103N10 | ZFIN Curated Data | |
| Encodes | EST | cb666 | Thisse et al., 2001 | |
| Encodes | STS | chunp30194 | ||
| Encodes | cDNA | MGC:85753 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:100919 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002748 (1) | 1493 nt | ||
| Genomic | GenBank:BX005025 (1) | 196375 nt | ||
| Polypeptide | UniProtKB:Q6NWG0 (1) | 243 aa |
No data available
- Vöcking, O., Famulski, J.K. (2023) A temporal single cell transcriptome atlas of zebrafish anterior segment development. Scientific Reports. 13:56565656
- McCluskey, B.M., Uji, S., Mancusi, J.L., Postlethwait, J.H., Parichy, D.M. (2021) A complex genetic architecture in zebrafish relatives Danio quagga and D. kyathit underlies development of stripes and spots. PLoS Genetics. 17:e1009364
- Dooley, C.M., Wali, N., Sealy, I.M., White, R.J., Stemple, D.L., Collins, J.E., Busch-Nentwich, E.M. (2019) The gene regulatory basis of genetic compensation during neural crest induction. PLoS Genetics. 15:e1008213
- Inoue, S., Kondo, S., Parichy, D.M., Watanabe, M. (2014) Tetraspanin 3c requirement for pigment cell interactions and boundary formation in zebrafish adult pigment stripes. Pigment cell & melanoma research. 27:190-200
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Ferrante, M.I., Romio, L., Castro, S., Collins, J.E., Goulding, D.A., Stemple, D.L., Woolf, A.S., and Wilson, S.W. (2009) Convergent Extension Movements and Ciliary Function are Mediated by ofd1, A Zebrafish Orthologue of the Human Oral-Facial-Digital Type 1 Syndrome Gene. Human molecular genetics. 18(2):289-303
- Engeszer, R.E., Wang, G., Ryan, M.J., and Parichy, D.M. (2008) Sex-specific perceptual spaces for a vertebrate basal social aggregative behavior. Proceedings of the National Academy of Sciences of the United States of America. 105(3):929-933
- Leung, Y.F., Ma, P., and Dowling, J.E. (2007) Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Investigative ophthalmology & visual science. 48(2):881-890
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Pujic, Z., Omori, Y., Tsujikawa, M., Thisse, B., Thisse, C., and Malicki, J. (2006) Reverse genetic analysis of neurogenesis in the zebrafish retina. Developmental Biology. 293(2):330-347
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