Gene

ift81

ID
ZDB-GENE-040714-3
Name
intraflagellar transport 81 homolog
Symbol
ift81 Nomenclature History
Previous Names
  • cdv1 (1)
  • larry (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have tubulin binding activity. Involved in pronephros development and regulation of TOR signaling. Predicted to localize to centrosome; cilium; and intraciliary transport particle B. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 19 with or without polydactyly. Is expressed in notochord; otic vesicle; pronephric duct; and ventricular system. Orthologous to human IFT81 (intraflagellar transport 81).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Sun et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift81 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
short-rib thoracic dysplasia 19 with or without polydactyly Alliance Short-rib thoracic dysplasia 19 with or without polydactyly 617895
Associated With ift81 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR041146 IFT81, calponin homology domain
Family IPR029600 Intraflagellar transport protein 81
Homologous_superfamily IPR043016 IFT81, N-terminal domain superfamily
Domain Details Per Protein
Protein Length IFT81, calponin homology domain IFT81, N-terminal domain superfamily Intraflagellar transport protein 81
UniProtKB:Q561Q6 245
UniProtKB:A4VCF5 259
UniProtKB:A9C3Q6 675
UniProtKB:Q6IVW2 675
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations