ZFIN is now using GRCz12tu for Genomic Data
Gene
gcgb
- ID
- ZDB-GENE-040712-2
- Name
- glucagon b
- Symbol
- gcgb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable glucagon receptor binding activity and hormone activity. Predicted to be involved in several processes, including intracellular glucose homeostasis; positive regulation of gluconeogenesis; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in glucagon secreting cell and pancreatic A cell. Human ortholog(s) of this gene implicated in Alzheimer's disease and prediabetes syndrome. Orthologous to human GCG (glucagon).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glucagon | Glucagon/GIP/secretin/VIP |
|---|---|---|---|---|
| UniProtKB:B0R1C3 | InterPro | 124 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers