Gene
prdm5
- ID
- ZDB-GENE-040708-1
- Name
- PR domain containing 5
- Symbol
- prdm5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA binding activity; histone methyltransferase binding activity; and repressing transcription factor binding activity. Involved in embryonic cranial skeleton morphogenesis; regulation of Wnt signaling pathway; and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in head; intestinal epithelium; nervous system; and pectoral fin. Orthologous to human PRDM5 (PR/SET domain 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| brittle cornea syndrome 2 | Alliance | Brittle cornea syndrome 2 | 614170 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001214 | SET domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR044415 | PRDM5, PR/SET domain |
| Family | IPR017125 | PR-domain zinc finger protein PRDM5-like |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Length | PRDM5, PR/SET domain | PR-domain zinc finger protein PRDM5-like | SET domain | SET domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q8J8
|
634 |
- Genome Browsers
Interactions and Pathways
Plasmids
No data available