ZFIN is now using GRCz12tu for Genomic Data
Gene
pnp4a
- ID
- ZDB-GENE-040625-83
- Name
- purine nucleoside phosphorylase 4a
- Symbol
- pnp4a Nomenclature History
- Previous Names
-
- zgc:86889 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable purine-nucleoside phosphorylase activity. Predicted to be involved in NAD+ biosynthetic process via the salvage pathway and purine nucleoside catabolic process. Predicted to act upstream of or within purine ribonucleoside salvage. Predicted to be active in cytosol. Is expressed in several structures, including eye; integument; iridoblast; neural crest; and optic vesicle.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6904627 (22 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Deis et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018099 | Purine phosphorylase, family 2, conserved site |
| Domain | IPR000845 | Nucleoside phosphorylase domain |
| Family | IPR011268 | Purine nucleoside phosphorylase |
| Family | IPR011270 | Purine nucleoside phosphorylase I, inosine/guanosine-specific |
| Family | IPR029236 | Protein of unknown function DUF4618 |
| Homologous_superfamily | IPR035994 | Nucleoside phosphorylase superfamily |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers