Gene
trnt1
- ID
- ZDB-GENE-040625-176
- Name
- tRNA nucleotidyl transferase, CCA-adding, 1
- Symbol
- trnt1 Nomenclature History
- Previous Names
-
- zgc:86645
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity and nucleotidyltransferase activity. Involved in several processes, including tRNA processing; thigmotaxis; and visual behavior. Used to study sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Human ortholog(s) of this gene implicated in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Is expressed in brain; heart; pectoral fin; retina; and trunk. Orthologous to human TRNT1 (tRNA nucleotidyl transferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6893785 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay | Alliance | Sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay | 616084 |
| Retinitis pigmentosa and erythrocytic microcytosis | 616959 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Nucleotidyltransferase superfamily | Poly A polymerase, head domain | tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain |
|---|---|---|---|---|
|
UniProtKB:F6NXI9
|
431 |
Interactions and Pathways
No data available
Plasmids
No data available