Gene

trnt1

ID
ZDB-GENE-040625-176
Name
tRNA nucleotidyl transferase, CCA-adding, 1
Symbol
trnt1 Nomenclature History
Previous Names
  • zgc:86645
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and nucleotidyltransferase activity. Involved in several processes, including tRNA processing; thigmotaxis; and visual behavior. Used to study sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Human ortholog(s) of this gene implicated in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Is expressed in brain; heart; pectoral fin; retina; and trunk. Orthologous to human TRNT1 (tRNA nucleotidyl transferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trnt1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay Alliance Sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay 616084
Retinitis pigmentosa and erythrocytic microcytosis 616959
Associated With trnt1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002646 Poly A polymerase, head domain
Domain IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain
Homologous_superfamily IPR043519 Nucleotidyltransferase superfamily
Domain Details Per Protein
Protein Length Nucleotidyltransferase superfamily Poly A polymerase, head domain tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain
UniProtKB:A0A2R8RYZ2 431
UniProtKB:Q6IQR7 405
UniProtKB:F6NXI9 431
UniProtKB:Q6DRP1 405
UniProtKB:A7MCH7 405
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations