ZFIN is now using GRCz12tu for Genomic Data

Gene

psmd4a

ID

ZDB-GENE-040625-104

Name

proteasome 26S subunit ubiquitin receptor, non-ATPase 4a

Symbol

psmd4a Nomenclature History

Previous Names

psmd4 (1)
fj42d12
wu:fj42d12
zgc:86833

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, base subcomplex. Predicted to be active in nucleus. Orthologous to human PSMD4 (proteasome 26S subunit ubiquitin receptor, non-ATPase 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6902324 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With psmd4a Human Ortholog

No data available

Associated With psmd4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003903	Ubiquitin interacting motif
Domain	IPR002035	von Willebrand factor, type A
Domain	IPR049590	PSMD4, RAZUL domain
Family	IPR027040	26S proteasome non-ATPase regulatory subunit 4
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	26S proteasome non-ATPase regulatory subunit 4	PSMD4, RAZUL domain	Ubiquitin interacting motif	von Willebrand factor A-like domain superfamily	von Willebrand factor, type A
UniProtKB:Q6IQC6	InterPro	372

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	psmd4 (1 of many)-201 (1) Ensembl	Ensembl	445 nt	Select Tool ZFIN BLAST
mRNA	psmd4a-201 (1) Ensembl	Ensembl	1,392 nt	Select Tool ZFIN BLAST
mRNA	psmd4a-202 (1) Ensembl	Ensembl	678 nt	Select Tool ZFIN BLAST
ncRNA	psmd4a-003 (1) Ensembl	Ensembl	746 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations