Gene
serac1
- ID
- ZDB-GENE-040616-1
- Name
- serine active site containing 1
- Symbol
- serac1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in endoplasmic reticulum; membrane; and mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome. Orthologous to human SERAC1 (serine active site containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome | Alliance | 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome | 614739 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Armadillo-like helical | Armadillo-type fold |
|---|---|---|---|---|
|
UniProtKB:Q5SNQ7
|
||||
|
UniProtKB:B7ZVR2
|
658 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
serac1-201
(1)
|
2769 nt |
Interactions and Pathways
No data available
Plasmids
No data available