nrp2a

ID

ZDB-GENE-040611-2

Name

neuropilin 2a

Symbol

nrp2a Nomenclature History

Previous Names

npn-2A (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Enables identical protein binding activity. Acts upstream of or within neural crest cell migration; regulation of vascular endothelial growth factor receptor signaling pathway; and vasculogenesis. Predicted to be located in membrane. Predicted to be active in axon; glutamatergic synapse; and postsynaptic membrane. Is expressed in axial vasculature; bulbus arteriosus; cranial neural crest cell; fin bud; and nervous system. Orthologous to human NRP2 (neuropilin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

18 figures from 15 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Hermans et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nrp2a Human Ortholog

No data available

Associated With nrp2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000421	Coagulation factor 5/8, C-terminal domain
Domain	IPR000859	CUB domain
Domain	IPR000998	MAM domain
Domain	IPR022579	Neuropilin, C-terminal
Family	IPR014648	Neuropilin
Family	IPR050633	Neuropilin/Multicopper Oxidase/Coagulation Factor
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR035914	Spermadhesin, CUB domain superfamily