Gene

asic1a

ID
ZDB-GENE-040513-2
Name
acid-sensing (proton-gated) ion channel 1a
Symbol
asic1a Nomenclature History
Previous Names
  • zASIC1.2 (1)
  • accn2b
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Enables ligand-gated sodium channel activity. Predicted to be involved in cellular response to pH and sodium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport and sodium ion transport. Located in plasma membrane. Is expressed in brain; eye; and gill. Orthologous to human ASIC1 (acid sensing ion channel subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa14670Allele with one point mutationUnknownPremature StopENU
sa21190Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With asic1a Human Ortholog
No data available
Associated With asic1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020903 Epithelial sodium channel, conserved site
Family IPR001873 Epithelial sodium channel
Family IPR004724 Epithelial sodium channel, chordates
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Epithelial sodium channel Epithelial sodium channel, chordates Epithelial sodium channel, conserved site
UniProtKB:Q708S7 InterPro 501
UniProtKB:A0A8M9QIQ3 InterPro 614
UniProtKB:B0R1B0 InterPro 501
1 - 3 of 3
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 8
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA asic1a-201 (1) Ensembl 3,385 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-255G12ZFIN Curated Data
EncodescDNAMGC:193950ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanASIC112
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
MouseAsic115
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 10
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