Gene

otud6b

ID
ZDB-GENE-040426-974
Name
OTU deubiquitinase 6B
Symbol
otud6b Nomenclature History
Previous Names
  • zgc:56305
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable cysteine-type deubiquitinase activity. Acts upstream of or within antiviral innate immune response. Is expressed in several structures, including gill; heart; liver; muscle; and pleuroperitoneal region. Orthologous to several human genes including OTUD6B (OTU deubiquitinase 6B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zhou et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otud6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with dysmorphic facies, seizures, and distal limb anomalies 617452
1 - 1 of 1
Associated With otud6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003323 OTU domain
Domain IPR049772 OTU domain-containing protein 6A/6B, ovarian tumor domain
Family IPR050704 Peptidase C85-like
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length OTU domain OTU domain-containing protein 6A/6B, ovarian tumor domain Papain-like cysteine peptidase superfamily Peptidase C85-like
UniProtKB:Q7ZV00 InterPro 293
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA otud6b-202 (1) Ensembl 1,359 nt
ncRNA otud6b-002 (1) Ensembl 854 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations