Gene

sulf2a

ID
ZDB-GENE-040426-759
Name
sulfatase 2a
Symbol
sulf2a Nomenclature History
Previous Names
  • sulf2
  • zgc:55612 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Acts upstream of or within with a positive effect on epithelial structure maintenance and oligodendrocyte development. Acts upstream of or within with a negative effect on ventral spinal cord interneuron differentiation. Predicted to be located in Golgi stack and extracellular space. Predicted to be active in cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including central nervous system; head; hypochord; neural plate; and neural tube. Orthologous to human SULF2 (sulfatase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sulf2a Human Ortholog
No data available
Associated With sulf2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR024607 Sulfatase, conserved site
Domain IPR000917 Sulfatase, N-terminal
Domain IPR024609 Extracellular sulfatase, C-terminal
Family IPR014615 Extracellular sulfatase
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily Extracellular sulfatase Extracellular sulfatase, C-terminal Sulfatase, conserved site Sulfatase, N-terminal
UniProtKB:Q7ZVU8 873
UniProtKB:A0A2R8PYV9 861
UniProtKB:A5WUS2 873
UniProtKB:A5WUS1 191
UniProtKB:A5WUS0 60
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations