Gene
sulf2a
- ID
- ZDB-GENE-040426-759
- Name
- sulfatase 2a
- Symbol
- sulf2a Nomenclature History
- Previous Names
-
- sulf2
- zgc:55612 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to be involved in several processes, including glomerular basement membrane development; positive regulation of vascular endothelial growth factor production; and regulation of signal transduction. Predicted to localize to cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including central nervous system; head; hypochord; neural plate; and neural tube. Orthologous to human SULF2 (sulfatase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55612 (13 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alkaline-phosphatase-like, core domain superfamily | Extracellular sulfatase | Extracellular sulfatase, C-terminal | Sulfatase, conserved site | Sulfatase, N-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QHJ3
|
765 | |||||
|
UniProtKB:Q7ZVU8
|
873 | |||||
|
UniProtKB:A0A8M2BGI3
|
874 | |||||
|
UniProtKB:A0A8M9QLI6
|
873 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
sulf2a-201
(1)
|
Havana | 3651 nt | |
| mRNA |
sulf2a-202
(1)
|
Havana | 774 nt | |
| mRNA |
sulf2a-203
(1)
|
Havana | 405 nt | |
| ncRNA |
sulf2a-002
(1)
|
Havana | 582 nt |
Interactions and Pathways
No data available
Plasmids
No data available