ZFIN is now using GRCz12tu for Genomic Data
Gene
ctu1
- ID
- ZDB-GENE-040426-704
- Name
- cytosolic thiouridylase subunit 1 homolog (S. pombe)
- Symbol
- ctu1 Nomenclature History
- Previous Names
-
- zgc:55395
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Predicted to act upstream of or within glycoprotein biosynthetic process; lipid metabolic process; and tRNA processing. Predicted to be located in cytosol. Predicted to be part of cytosolic tRNA wobble base thiouridylase complex. Orthologous to human CTU1 (cytosolic thiouridylase subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55395 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020554 | Uncharacterised protein family UPF0021, conserved site |
| Domain | IPR011063 | tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal |
| Domain | IPR031481 | Fucosyltransferase, N-terminal |
| Domain | IPR032442 | Cytoplasmic tRNA 2-thiolation protein 1, C-terminal |
| Domain | IPR055270 | Fucosyltransferase, C-terminal |
| Domain | IPR056369 | Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain |
| Family | IPR000541 | Cytoplasmic tRNA 2-thiolation protein 1 |
| Family | IPR001503 | Glycosyl transferase family 10 |
| Family | IPR035107 | tRNA thiolation protein, TtcA/Ctu1 type |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR038577 | GT10-like, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytoplasmic tRNA 2-thiolation protein 1 | Cytoplasmic tRNA 2-thiolation protein 1, C-terminal | Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain | Fucosyltransferase, C-terminal | Fucosyltransferase, N-terminal | Glycosyl transferase family 10 | GT10-like, C-terminal domain superfamily | Rossmann-like alpha/beta/alpha sandwich fold | tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal | tRNA thiolation protein, TtcA/Ctu1 type | Uncharacterised protein family UPF0021, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B2GNZ1 | InterPro | 343 | |||||||||||
| UniProtKB:A0A8M2BJT0 | InterPro | 358 | |||||||||||
| UniProtKB:Q803X1 | InterPro | 343 | |||||||||||
| UniProtKB:A0A8M6Z811 | InterPro | 372 | |||||||||||
| UniProtKB:A0AB32TWK5 | InterPro | 359 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers