Gene
uba3
- ID
- ZDB-GENE-040426-2825
- Name
- ubiquitin-like modifier activating enzyme 3
- Symbol
- uba3 Nomenclature History
- Previous Names
-
- ube1c (1)
- wu:fb75e04
- wu:fc37b11
- zgc:55528
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable NEDD8 activating enzyme activity. Predicted to be involved in protein neddylation. Predicted to be active in cytoplasm and nucleus. Is expressed in inner ear. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55528 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033127 | Ubiquitin-activating enzyme E1, Cys active site |
| Domain | IPR000594 | THIF-type NAD/FAD binding fold |
| Domain | IPR014929 | E2 binding |
| Domain | IPR030468 | NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain |
| Family | IPR045886 | ThiF/MoeB/HesA family |
| Homologous_superfamily | IPR023318 | Ubiquitin activating enzyme, alpha domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | E2 binding | NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin activating enzyme, alpha domain superfamily | Ubiquitin-activating enzyme E1, Cys active site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZVX6 | InterPro | 462 | ||||||
| UniProtKB:A0A8M2B283 | InterPro | 449 | ||||||
| UniProtKB:B2GSP4 | InterPro | 462 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available