Gene
uba3
- ID
- ZDB-GENE-040426-2825
- Name
- ubiquitin-like modifier activating enzyme 3
- Symbol
- uba3 Nomenclature History
- Previous Names
-
- ube1c (1)
- wu:fb75e04
- wu:fc37b11
- zgc:55528
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable NEDD8 activating enzyme activity. Predicted to be involved in protein neddylation. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Is expressed in inner ear. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55528 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033127 | Ubiquitin-activating enzyme E1, Cys active site |
| Domain | IPR000594 | THIF-type NAD/FAD binding fold |
| Domain | IPR014929 | E2 binding |
| Domain | IPR030468 | NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain |
| Family | IPR045886 | ThiF/MoeB/HesA family |
| Homologous_superfamily | IPR023318 | Ubiquitin activating enzyme, alpha domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | E2 binding | NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin activating enzyme, alpha domain superfamily | Ubiquitin-activating enzyme E1, Cys active site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZVX6 | InterPro | 462 | ||||||
| UniProtKB:A0A8M2B283 | InterPro | 449 | ||||||
| UniProtKB:B2GSP4 | InterPro | 462 |
Interactions and Pathways
No data available
Plasmids
No data available