Gene

srsf6a

ID
ZDB-GENE-040426-2824
Name
serine and arginine rich splicing factor 6a
Symbol
srsf6a Nomenclature History
Previous Names
  • sfrs6a
  • fa12h12
  • wu:fa12h12
  • wu:fa13e06
  • zgc:63770 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to enable mRNA binding activity. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Orthologous to human SRSF6 (serine and arginine rich splicing factor 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa32423Allele with one point mutationUnknownPremature StopENU
1 - 1 of 1
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-srsf6a
    Lv et al., 2025
    1 - 1 of 1
    Show
    Human Disease
    Associated With srsf6a Human Ortholog
    No data available
    Associated With srsf6a Via Experimental Models
    No data available
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Domain IPR000504 RNA recognition motif domain
    Domain IPR047190 Serine/arginine-rich splicing factor 4/6, RNA recognition motif 2
    Family IPR050374 RRT5/SRSF/Splicing Factor SR
    Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    Homologous_superfamily IPR035979 RNA-binding domain superfamily
    1 - 5 of 5
    Domain Details Per Protein
    Protein Additional Resources Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain RRT5/SRSF/Splicing Factor SR Serine/arginine-rich splicing factor 4/6, RNA recognition motif 2
    UniProtKB:A0A8M9PT05 InterPro 246
    UniProtKB:A0A8M2B8T5 InterPro 400
    UniProtKB:Q7SXU9 InterPro 347
    1 - 3 of 3
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 23
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA srsf6a-201 (1) Ensembl 1,561 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    No data available
    Plasmids
    No data available
    Constructs
    No data available
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH211-10D23ZFIN Curated Data
    EncodesESTfa12h12
    EncodesESTfa13e06ZFIN Curated Data
    EncodescDNAMGC:63770ZFIN Curated Data
    1 - 4 of 4
    Show
    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanSRSF620
    Phylogenetic tree (1)
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    MouseSrsf62
    Phylogenetic tree (1)
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
    1 - 6 of 6
    Show