Gene
plrg1
- ID
- ZDB-GENE-040426-2787
- Name
- pleiotropic regulator 1
- Symbol
- plrg1 Nomenclature History
- Previous Names
-
- wu:fi74f01
- zgc:55651
- zgc:86603
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator and negative regulation of apoptotic process. Predicted to colocalize with DNA replication factor A complex. Orthologous to human PLRG1 (pleiotropic regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138004 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR045241 | WD repeat Prp46/PLRG1-like |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat Prp46/PLRG1-like |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DRE2
|
511 |
Interactions and Pathways
No data available
Plasmids
No data available