Gene
fez1
- ID
- ZDB-GENE-040426-2723
- Name
- fasciculation and elongation protein zeta 1 (zygin I)
- Symbol
- fez1 Nomenclature History
- Previous Names
-
- wu:fj14c12
- zgc:73258
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to be active in axon and cytoplasm. Is expressed in nervous system and neural tube. Orthologous to human FEZ1 (fasciculation and elongation protein zeta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73258 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR011680 | Fasciculation and elongation protein zeta, FEZ |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Fasciculation and elongation protein zeta, FEZ |
|---|---|---|---|
| UniProtKB:Q6PBT3 | InterPro | 394 | |
| UniProtKB:A0A8M3AWU2 | InterPro | 378 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-80M8 | ZFIN Curated Data | |
| Encodes | EST | fj14c12 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:73258 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213396 (1) | 2176 nt | ||
| Genomic | GenBank:CR932979 (1) | 177139 nt | ||
| Polypeptide | UniProtKB:Q6PBT3 (1) | 394 aa |
- Haws, W., England, S., Grieb, G., Susana, G., Hernandez, S., Mirer, H., Lewis, K. (2023) Analyses of binding partners and functional domains for the developmentally essential protein Hmx3a/HMX3. Scientific Reports. 13:11511151
- Lee, H.J., Hou, Y., Maeng, J.H., Shah, N.M., Chen, Y., Lawson, H.A., Yang, H., Yue, F., Wang, T. (2022) Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish. Genome research. 32(7):1424-1436
- Messina, A., Boiti, A., Vallortigara, G. (2020) Asymmetric distribution of pallial-expressed genes in zebrafish (Danio rerio). The European journal of neuroscience. 53(2):362-375
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Aoki, M., Segawa, H., Naito, M., and Okamoto, H. (2014) Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons. Biochemical and Biophysical Research Communications. 445(2):357-362
- Andersen, I.S., Reiner, A.H., Aanes, H., Alestrom, P., and Collas, P. (2012) Developmental features of DNA methylation during activation of the embryonic zebrafish genome. Genome biology. 13(7):R65
- Ritter, D.I., Dong, Z., Guo, S., and Chuang, J.H. (2012) Transcriptional enhancers in protein-coding exons of vertebrate developmental genes. PLoS One. 7(5):e35202
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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