ZFIN is now using GRCz12tu for Genomic Data
Gene
nsun5
- ID
- ZDB-GENE-040426-2476
- Name
- NOP2/Sun RNA methyltransferase 5
- Symbol
- nsun5 Nomenclature History
- Previous Names
-
- wu:fc49f12
- zgc:66176
- zgc:77183 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable rRNA (cytosine-C5-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be active in nucleolus. Orthologous to several human genes including NSUN5 (NOP2/Sun RNA methyltransferase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77183 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001678 | SAM-dependent methyltransferase RsmB-F/NOP2-type domain |
| Domain | IPR048889 | NSUN5/RCM1, N-terminal domain |
| Domain | IPR049560 | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core |
| Domain | IPR049561 | NOL1/NOP2/NSUN 5/7, ferredoxin-like domain |
| Family | IPR023267 | RNA (C5-cytosine) methyltransferase |
| Homologous_superfamily | IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | NOL1/NOP2/NSUN 5/7, ferredoxin-like domain | NSUN5/RCM1, N-terminal domain | RNA (C5-cytosine) methyltransferase | S-adenosyl-L-methionine-dependent methyltransferase superfamily | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core | SAM-dependent methyltransferase RsmB-F/NOP2-type domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NZ28 | InterPro | 435 | ||||||
| UniProtKB:A0A8M3BD27 | InterPro | 483 | ||||||
| UniProtKB:A0AC58GJ64 | InterPro | 343 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers