Gene

sfpq

ID

ZDB-GENE-040426-2452

Name

splicing factor proline/glutamine-rich

Symbol

sfpq Nomenclature History

Previous Names

hm:zeh0027
wis (1)
wu:fa11h12
wu:fd10f03
zgc:85935

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have transcription regulatory region sequence-specific DNA binding activity. Involved in nervous system development. Localizes to neuron projection and nucleus. Is expressed in brain; eye; gut; heart; and muscle cell. Orthologous to human SFPQ (splicing factor proline and glutamine rich).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:85935 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 21 figures from 10 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sfpq Human Ortholog

No data available

Associated With sfpq Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR012975	NOPS
Domain	IPR034525	PSF, RNA recognition motif 1
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	NOPS	Nucleotide-binding alpha-beta plait domain superfamily	PSF, RNA recognition motif 1	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:Q6NUU2 InterPro	619

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	sfpq-204 (1) Ensembl	Havana	2273 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sfpq-201 (1) Ensembl	Havana	2424 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	sfpq-202 (1) Ensembl	Havana	688 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	sfpq-003 (1) Ensembl	Havana	818 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations