ZFIN is now using GRCz12tu for Genomic Data
Gene
kdm2ba
- ID
- ZDB-GENE-040426-2195
- Name
- lysine (K)-specific demethylase 2Ba
- Symbol
- kdm2ba Nomenclature History
- Previous Names
-
- wu:fd13a09
- zgc:85787
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA binding activity; histone H3K36me/H3K36me2 demethylase activity; and zinc ion binding activity. Predicted to be involved in chromatin remodeling. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with congenital cardiac defects and variable renal and ocular abnormalities. Orthologous to human KDM2B (lysine demethylase 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with congenital cardiac defects and variable renal and ocular abnormalities | Alliance | Neurodevelopmental disorder with congenital cardiac defects and variable renal and ocular abnormalities | 621474 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001810 | F-box domain |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR002857 | Zinc finger, CXXC-type |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Family | IPR050690 | JHDM1 Histone Demethylase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | F-box domain | JHDM1 Histone Demethylase | Leucine-rich repeat domain superfamily | Zinc finger, CXXC-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NUY1 | InterPro | 411 | |||||||||
| UniProtKB:A0A8M9Q9M7 | InterPro | 870 | |||||||||
| UniProtKB:F1QE63 | InterPro | 873 | |||||||||
| UniProtKB:A0A8M9Q3E1 | InterPro | 872 | |||||||||
| UniProtKB:A0A8M1PGH3 | InterPro | 871 | |||||||||
| UniProtKB:A0AB32TVP0 | InterPro | 872 | |||||||||
| UniProtKB:A0AC58G6M8 | InterPro | 869 | |||||||||
| UniProtKB:A0AB32U022 | InterPro | 873 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kdm2ba-201
(1)
|
Ensembl | 3,247 nt | ||
| mRNA |
kdm2ba-202
(1)
|
Ensembl | 3,247 nt | ||
| mRNA |
kdm2ba-203
(1)
|
Ensembl | 3,484 nt | ||
| mRNA |
kdm2ba-204
(1)
|
Ensembl | 7,045 nt | ||
| mRNA |
kdm2ba-205
(1)
|
Ensembl | 7,012 nt | ||
| mRNA |
kdm2ba-206
(1)
|
Ensembl | 7,394 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers