Gene
cyb5a
- ID
- ZDB-GENE-040426-2148
- Name
- cytochrome b5 type A (microsomal)
- Symbol
- cyb5a Nomenclature History
- Previous Names
-
- wu:fb44a11
- zgc:64123
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Enables heme binding activity and oxidoreductase activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle and membrane. Is expressed in digestive system; head; immature eye; neural crest; and optic stalk. Human ortholog(s) of this gene implicated in methemoglobinemia and methemoglobinemia and ambiguous genitalia. Orthologous to human CYB5A (cytochrome b5 type A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64123 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| methemoglobinemia and ambiguous genitalia | Alliance | Methemoglobinemia and ambiguous genitalia | 250790 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome b5 | Cytochrome b5, heme-binding site | Cytochrome b5-like heme/steroid binding domain | Cytochrome b5-like heme/steroid binding domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A8WGS0 | InterPro | 137 | ||||
| UniProtKB:Q7T341 | InterPro | 137 |
1 - 2 of 2
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available