ZFIN is now using GRCz12tu for Genomic Data
Gene
tead1a
- ID
- ZDB-GENE-040426-2101
- Name
- TEA domain family member 1a
- Symbol
- tead1a Nomenclature History
- Previous Names
-
- tead1
- zgc:63696
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including Kupffer's vesicle development; cilium assembly; and determination of heart left/right asymmetry. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in nervous system; neural plate; and somite. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to human TEAD1 (TEA domain transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63696 (23 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Fillatre et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sveinsson chorioretinal atrophy | Alliance | Sveinsson chorioretinal atrophy | 108985 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | TEA/ATTS domain | TEA/ATTS domain superfamily | TEC1/TEAD Transcription Factor | Transcriptional enhancer factor, metazoa | YAP binding domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B730 | InterPro | 422 | |||||
| UniProtKB:Q7SXX3 | InterPro | 393 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tead1a-201
(1)
|
Ensembl | 748 nt | ||
| mRNA |
tead1a-202
(1)
|
Ensembl | 1,744 nt | ||
| ncRNA |
tead1a-003
(1)
|
Ensembl | 817 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers