Gene
sdf4
- ID
- ZDB-GENE-040426-2061
- Name
- stromal cell derived factor 4
- Symbol
- sdf4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in Golgi lumen. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including epidermis; hatching gland; notochord; periderm; and polster. Orthologous to human SDF4 (stromal cell derived factor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56577 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Delcourt et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Targeting Reagent | Created Alleles | Citations |
---|---|---|
MO1-sdf4 | N/A | Delcourt et al., 2015 |
MO2-sdf4 | N/A | Delcourt et al., 2015 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Calcium-binding protein CAB45, EF-hand | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair |
---|---|---|---|---|---|---|
UniProtKB:Q7ZUC2 | InterPro | 356 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-31B16 | ZFIN Curated Data | |
Encodes | EST | fb66d06 | ||
Encodes | EST | fd46e11 | ||
Encodes | cDNA | MGC:56577 | ||
Encodes | cDNA | MGC:76916 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_213087 (1) | 2406 nt | ||
Genomic | GenBank:BX957326 (1) | 259092 nt | ||
Polypeptide | UniProtKB:Q7ZUC2 (1) | 356 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Delcourt, N., Quevedo, C., Nonne, C., Fons, P., O'Brien, D., Loyaux, D., Diez, M., Autelitano, F., Guillemot, J.C., Ferrara, P., Muriana, A., Callol, C., Hérault, J.P., Herbert, J.M., Favre, G., Bono, F. (2015) Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis. The Journal of biological chemistry. 290(6):3405-17
- Fernández, J.A., Bubner, E.J., Takeuchi, Y., Yoshizaki, G., Wang, T., Cummins, S.F., Elizur, A. (2015) Primordial germ cell migration in the yellowtail kingfish (Seriola lalandi) and identification of stromal cell-derived factor 1. General and comparative endocrinology. 213:16-23
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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